“Abram Hoffer, MD PhD” with “Margot Kidder” – Masks of Madness Science of Healing 1998 Documentary of Dr. Abram Hoffer. Vitamin B3(Niacin) for alleviating mental disorders.

Abram Hoffer, MD, PhD (1917-2009), a founder of Orthomolecular Medicine, (with Double Nobel Prize Winner Dr. Linus Pauling) was a world-renowned Canadian doctor and biochemist that treated over five thousands of patients with mental disorders (including schizophrenia, drug/alcohol addiction, psychosis) through better nutrition , micronutrients, and megavitamin therapy. Dr. Abram Hoffer, a pioneer of holistic nutritional/vitamin therapy, died in May 2009 at the age of 91. For over 50 years, Dr. Abram Hoffer personally took 4,500 mg (4.5 grams) of Niacin (Vitamin B-3) along with other supplements. Dr Abram Hoffer was a prolific researcher and writer, wrote over 30 books and 600 peer-reviewed medical journal articles (most of which were ignored by mainstream medicine) and was productive until 2 weeks prior to his death (age 91).

Mary MacIsaac (1893-2006): Oldest Person in Canada , Age 112, Friend of Dr. Abram Hoffer
Oldest human in Canada, Canadian Supercentenarian, Mary MacIsaac (27 December 1893 – 10 March 2006) was a friend of Dr. Abram Hoffer . Ms. Mary MacIsaac, Canadian’s oldest person, age 112, died on March 10, 2006. Mary MacIsaac was Canada’s oldest person and 19th-oldest in the world. But Mary MacIsaac differed significantly from the others, for Ms. MacIsaac had been taking niacin for forty years before she died. Ms. Mary MacIsaac had cross-country skied until 110 and was photographed playing a piano duet with her great-grandson just before she died. Ms. MacIsaac was weaker, but her mind was clear when she died after a brief illness. Mary MacIsaac credited the Niacin and perhaps she was correct, because Niacin (vitamin B-3) does have remarkable anti-aging and life-extending properties, according to Dr. Abram Hoffer.

Alcoholics Anonymous (AA) and Dr. Abram Hoffer
The founder of AA (Alcoholics Anonymous), “Bill W” (Bill Wilson) was a friend of Dr. Abram Hoffer, and followed Abram Hoffer’s program for many years . “Bill W” (Bill Wilson) took 3000 mg of Vitamin B3 (Niacin) and 3000 mg of Vitamin C , daily.

Here is a SUMMARY of Dr Abram Hoffer’s BASIC recommended vitamin therapy for schizophrenia, paranoia, bipolar disorder, ADD, ADHD, anxiety disorder, panic attacks, depression, OCD (obsessive-compulsive disorder), psychosis, alcoholism, addictions, anorexia nervosa, autism spectrum disorder , PTSD, insomnia:


1) Vitamin B3 (niacin or niacinamide) 1000 mg three times per day.

2) Multivitamin (without iron) , once a day

3) Vitamin C, 1000 mg three times per day .

4) B-50 Complex tablet three times per day.


1) Vitamin D3 5000 IU per day

2) Vitamin E 400 IU three times per day

3) Zinc 50 mg per day

4) Selenium 200 mcg per day

5) Calcium 1000 mg and Magnesium 500 mg

6) Salmon Oil (Omega-3 Fish Oil) 1000 mg three times per day

7) NAC (N-Acetyl-Cysteine) 1000 mg two times per day

– Turmeric (Curcumin) , 1 to 3 times per day
– Ginkgo BIloba , 1 to 3 times per day
– Bacopa monnieri (Brahmi) , 1 to 3 times per day

For Vitamin B3, start with 250 mg Vitamin B-3 (niacin) daily after a meal for 7 days, then gradually increase the dose at seven day intervals, over four to six weeks, to reach the target dose of 1 gram
three times per day.

NOTE: Vitamin B3 (in form of Niacin) may cause a “warm pleasurable flushing” sensation in face or hands, at the beginning of use – this flushing is safe and many people enjoy this “warm sensation”. It might take 3 to 4 weeks to see results.

Eat whole foods. No sugar, white flours, junk foods. Dr. Abram Hoffer advocated no-sugar, no-flour, a low carbohydrate “junk food-free” or “paleolithic” diet, and later became convinced that certain foods and artificial food additives (artificial food coloring, artificial food preservative) could have important adverse cognitive effects in specific psychotic patients.

“Linus Pauling”
Abram Hoffer, “Margot Kidder”, “bipolar disorder”, Hugh Riordan, Hyla Cass,

Abram Hoffer, MD, PhD – natural vitamin treatment for: attention deficit and hyperactivity disorder (ADHD), disruptive mood dysregulation disorder, various specific phobias, social anxiety disorder (SAD), generalized anxiety disorder (GAD), obsessive compulsive disorder (OCD), separation anxiety disorder, oppositional defiant disorder (ODD), conduct disorder, learning disabilities, enuresis, encopresis, tics, Asperger’s, pervasive developmental disorders (PDD) including autism and autism spectrum disorders, bipolar disorder (including sub-types), depression and dysthymic disorders (including sub-types), panic disorders, Prader-Willi syndrome, psychoses, post-traumatic stress disorder (PTSD), insomnia, stress.